Semisynthetic Penicillin
نویسندگان
چکیده
منابع مشابه
New Semisynthetic Penicillin
Sodium 6{D(-)-a(4-hydroxyl-1,5 naphthyridine-3-carboxamido)phenylacetamido} penicillanate (PC-904) is a new semisynthetic penicillin with broadspectrum activity against gram-positive cocci and gram-negative bacilli. At a concentration of 1.56 ,ug/ml, it inhibited 100% of isolates of Proteus mirabilis, 89%o of Pseudomonas aeruginosa, 67% of Escherichia coli, and 45% of Enterobacter spp. At a con...
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CI-867, a new semisynthetic penicillin, has exhibited broad-spectrum activity in vitro against gram-positive cocci, except penicillin G-resistant Staphylococcus aureus, and against gram-negative bacilli. It was especially active against Pseudomonas aeruginosa and as active as mezlocillin and piperacillin against Klebsiella pneumoniae. CI-867 was bactericidal against most organisms. Its activity...
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The activity of azlocillin, a new semisynthetic penicillin, was determined against 582 clinical isolates of gram-negative bacilli and gram-positive cocci. Over 75% of the isolates of Pseudomonas aeruginosa were inhibited at a concentration of 12.5 mug or less per ml. Azlocillin is also active against indole-negative and -positive Proteus spp., inhibiting 98 and 71%, respectively, at a concentra...
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The activity of 6-[d(-)-alpha-carboxy-3-thienylacetamido] penicillanic acid, BRL2288, was determined against Pseudomonas aeruginosa and various gram-negative bacilli. The majority of Pseudomonas strains (89%) were inhibited by 100 mug of the antibiotic per ml. BRL2288 is twofold more active than carbenicillin against Pseudomonas at 100 mug/ml or less. Among Enterobacteriaceae tested, 87% Entero...
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T-1220, sodium 6-[d-(-)-alpha-(4-ethyl-2,3-dioxo-1-piperazinylcarbonyl-amino)- alpha-phenylacetamido] penicillanate, is a new semisynthetic penicillin derivative that possesses a broad spectrum of in vitro antibacterial activity against gram-positive and gram-negative bacteria. T-1220 is more effective than carbenicillin (CB-PC) against Pseudomonas aeruginosa, Klebsiella pneumoniae, Proteus spe...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1966
ISSN: 0002-1369,1881-1280
DOI: 10.1271/bbb1961.30.1047